Genomic Research Laboratory Geneva - Publications
Genomic Research Laboratory
Group of Prof. J. Schrenzel
Service of Infectious Diseases
Geneva University Hospitals (HUG)
CH-1211 Geneva 4, Switzerland

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Publications

   
           
       
   

Contribution of Clinical Metagenomics to the Diagnosis of Bone and Joint Infections
d'Humières C,Gaïa N,Gueye S,de Lastours V,Leflon-Guibout V,Maataoui N,Duprilot M,Lecronier M,Rousseau MA,Gamany N,Lescure FX,Senard O,Deconinck L,Dollat M,Isernia V,Le Hur AC,Petitjean M,Nazimoudine A,Le Gac S,Chalal S,Ferreira S,Lazarevic V,Guigon G,Gervasi G,Armand-Lefèvre L,Schrenzel J,Ruppé E
Front Microbiol. 2022 Apr 21;13:863777. doi: 10.3389/fmicb.2022.863777.
[Abstract] [PubMed]

Comparative genomics analysis of two Helcococcus kunzii strains co-isolated with Staphylococcus aureus from diabetic foot ulcers
Durand BARN,Yahiaoui Martinez A,Baud D,François P,Lavigne JP,Dunyach-Remy C
Genomics. 2022 Apr 9;114(3):110365. doi: 10.1016/j.ygeno.2022.110365.
[Abstract] [PubMed]

Bacteremia Detection in Second or Subsequent Blood Cultures Among Hospitalized Patients in a Tertiary Care Hospital
Zanella MC,de Lorenzi-Tognon M,Fischer A,Vernaz N,Schrenzel J
JAMA Netw Open. 2022 Apr 1;5(4):e228065. doi: 10.1001/jamanetworkopen.2022.8065.
[Abstract] [PubMed]

Agrobacterium species bacteraemia, Switzerland, 2008 to 2019: a molecular epidemiological study
Balmer L,Seth-Smith HMB,Egli A,Casanova C,Kronenberg A,Schrenzel J,Marschall J,Sommerstein R
Antimicrob Resist Infect Control. 2022 Mar 9;11(1):47. doi:
[Abstract] [PubMed]

Transcriptomic Analysis of E. coli after Exposure to a Sublethal Concentration of Hydrogen Peroxide Revealed a Coordinated Up-Regulation of the Cysteine Biosynthesis Pathway
Roth M,Jaquet V,Lemeille S,Bonetti EJ,Cambet Y,François P,Krause KH
Antioxidants (Basel). 2022 Mar 28;11(4):655. doi: 10.3390/antiox11040655.
[Abstract] [PubMed]

Total Laboratory Automation for Rapid Detection and Identification of Microorganisms and Their Antimicrobial Resistance Profiles
Cherkaoui A,Schrenzel J
Front Cell Infect Microbiol. 2022 Feb 3;12:807668. doi:
[Abstract] [PubMed]

Mycobacterium chelonae Infection Identified by Metagenomic Next-Generation Sequencing as the Probable Cause of Acute Contained Rupture of a Biological Composite Graft-A Case Report
Büchler AC,Lazarevic V,Gaïa N,Girard M,Eckstein F,Egli A,Sutter ST,Schrenzel J
Int J Mol Sci. 2021 Dec 29;23(1):381. doi: 10.3390/ijms23010381.
[Abstract] [PubMed]

Changes in the gut bacterial communities in colon cancer surgery patients: an observational study
Abbas M,Gaïa N,Buchs NC,Delaune V,Girard M,Andrey DO,Meyer J,Schrenzel J,Ris F,Harbarth S,Lazarevic V
Gut Pathog. 2022 Jan 4;14(1):2. doi: 10.1186/s13099-021-00477-7.
[Abstract] [PubMed]

Nontuberculous Mycobacteria under Scrutiny in the Geneva Area (2015-2020)
Vongthilath-Moeung R,Plojoux J,Poncet A,Renzi G,Veziris N,Schrenzel J,Janssens JP
Respiration. 2022;101(4):367-375. doi: 10.1159/000520033. Epub 2021 Dec 7.
[Abstract] [PubMed]



Two-Component Systems of S. aureus: Signaling and Sensing Mechanisms
Bleul L,Francois P,Wolz C
Genes (Basel). 2021 Dec 23;13(1):34. doi: 10.3390/genes13010034.
[Abstract] [PubMed]

Metataxonomic and Metabolic Impact of Fecal Microbiota Transplantation From Patients With Pancreatic Cancer Into Germ-Free Mice: A Pilot Study
Genton L,Lazarevic V,Stojanovic O,Spiljar M,Djaafar S,Koessler T,Dutoit V,Gaïa N,Mareschal J,Macpherson AJ,Herrmann F,Trajkovski M,Schrenzel J
Front Cell Infect Microbiol. 2021 Oct 19;11:752889. doi:
[Abstract] [PubMed]

Synthèse du 6 e symposium « Feeding the Microbiota »
Assouline-Reinmann M,Genton L,Schrenzel J
Rev Med Suisse. 2021 Oct 27;17(756):1855-1857.
[Abstract] [PubMed]

The Staphylococcus aureus CC398 Lineage: An Evolution Driven by the Acquisition of Prophages and Other Mobile Genetic Elements
Laumay F,Benchetrit H,Corvaglia AR,van der Mee-Marquet N,François P
Genes (Basel). 2021 Oct 30;12(11):1752. doi: 10.3390/genes12111752.
[Abstract] [PubMed]

Staphylococcusaureus Transcriptome Data and Metabolic Modelling Investigate the Interplay of Ser/Thr Kinase PknB, Its Phosphatase Stp, the glmR/yvcK Regulon and the cdaA Operon for Metabolic Adaptation
Liang C,Rios-Miguel AB,Jarick M,Neurgaonkar P,Girard M,François P,Schrenzel J,Ibrahim ES,Ohlsen K,Dandekar T
Microorganisms. 2021 Oct 14;9(10):2148. doi: 10.3390/microorganisms9102148.
[Abstract] [PubMed]

Epidemiology of ESBL-producing Escherichia coli from repeated prevalence studies over 11 years in a long-term-care facility
Martischang R,François P,Cherkaoui A,Gaïa N,Renzi G,Agostinho A,Perez M,Graf CE,Harbarth S
Antimicrob Resist Infect Control. 2021 Oct 19;10(1):148. doi:
[Abstract] [PubMed]

Trends of the Epidemiology of Candidemia in Switzerland: A 15-Year FUNGINOS Survey
Adam KM,Osthoff M,Lamoth F,Conen A,Erard V,Boggian K,Schreiber PW,Zimmerli S,Bochud PY,Neofytos D,Fleury M,Fankhauser H,Goldenberger D,Mühlethaler K,Riat A,Zbinden R,Kronenberg A,Quiblier C,Marchetti O,Khanna N
Open Forum Infect Dis. 2021 Sep 17;8(10):ofab471. doi: 10.1093/ofid/ofab471.
[Abstract] [PubMed]

Hydrogen Peroxide Affects Growth of S. aureus Through Downregulation of Genes Involved in Pyrimidine Biosynthesis
Buvelot H,Roth M,Jaquet V,Lozkhin A,Renzoni A,Bonetti EJ,Gaia N,Laumay F,Mollin M,Stasia MJ,Schrenzel J,François P,Krause KH
Front Immunol. 2021 Sep 7;12:673985. doi: 10.3389/fimmu.2021.673985. eCollection
[Abstract] [PubMed]

Gut barrier and microbiota changes with glycine and branched-chain amino acid supplementation in chronic haemodialysis patients
Genton L,Pruijm M,Teta D,Bassi I,Cani PD,Gaïa N,Herrmann FR,Marangon N,Mareschal J,Muccioli GG,Stoermann C,Suriano F,Wurzner-Ghajarzadeh A,Lazarevic V,Schrenzel J
J Cachexia Sarcopenia Muscle. 2021 Dec;12(6):1527-1539. doi: 10.1002/jcsm.12781.
[Abstract] [PubMed]

Glycine increases fat-free mass in malnourished haemodialysis patients: a randomized double-blind crossover trial
Genton L,Teta D,Pruijm M,Stoermann C,Marangon N,Mareschal J,Bassi I,Wurzner-Ghajarzadeh A,Lazarevic V,Cynober L,Cani PD,Herrmann FR,Schrenzel J
J Cachexia Sarcopenia Muscle. 2021 Dec;12(6):1540-1552. doi: 10.1002/jcsm.12780.
[Abstract] [PubMed]

Effects of antibiotic duration on the intestinal microbiota and resistome: The PIRATE RESISTANCE project, a cohort study nested within a randomized trial
Leo S,Lazarevic V,von Dach E,Kaiser L,Prendki V,Schrenzel J,Huttner BD,Huttner A
EBioMedicine. 2021 Sep;71:103566. doi: 10.1016/j.ebiom.2021.103566. Epub 2021 Sep
[Abstract] [PubMed]

Co-Carriage of Metal and Antibiotic Resistance Genes in Sewage Associated Staphylococci
Amirsoleimani A,Brion G,Francois P
Genes (Basel). 2021 Sep 23;12(10):1473. doi: 10.3390/genes12101473.
[Abstract] [PubMed]

Time to Detection of Growth for Mycobacterium tuberculosis in a Low Incidence Area
Vongthilath-Moeung R,Poncet A,Renzi G,Schrenzel J,Janssens JP
Front Cell Infect Microbiol. 2021 Aug 19;11:704169. doi:
[Abstract] [PubMed]

Outbreak of Pseudomonas aeruginosa producing VIM carbapenemase in an intensive care unit and its termination by implementation of waterless patient care.
Catho G,Martischang R,Boroli F,Chraïti MN,Martin Y,Koyluk Tomsuk Z,Renzi G,Schrenzel J,Pugin J,Nordmann P,Blanc DS,Harbarth S
Crit Care. 2021 Aug 19;25(1):301. doi: 10.1186/s13054-021-03726-y.
[Abstract] [PubMed]

Performance of Fully Automated Antimicrobial Disk Diffusion Susceptibility Testing Using Copan WASP Colibri Coupled to the Radian In-Line Carousel and Expert System.
Cherkaoui A,Renzi G,Vuilleumier N,Schrenzel J
J Clin Microbiol. 2021 Aug 18;59(9):e0077721. doi: 10.1128/JCM.00777-21. Epub 2021 Aug 18.
[Abstract] [PubMed]

The human gut mycobiome and the specific role of Candida albicans: where do we stand, as clinicians?
Musumeci S,Coen M,Leidi A,Schrenzel J
Clin Microbiol Infect. 2021 Aug 4:S1198-743X(21)00429-8. doi: 10.1016/j.cmi.2021.07.034.
[Abstract] [PubMed]

The Potential Role of Clinical Metagenomics in Infectious Diseases: Therapeutic Perspectives.
d'Humières C,Salmona M,Dellière S,Leo S,Rodriguez C,Angebault C,Alanio A,Fourati S,Lazarevic V,Woerther PL,Schrenzel J,Ruppé E
Drugs. 2021 Jul 30:1-14. doi: 10.1007/s40265-021-01572-4.
[Abstract] [PubMed]

Populations of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae are different in human-polluted environment and food items: A multicentre European study.
Martak D,Guther J,Verschuuren TD,Valot B,Conzelmann N,Bunk S,Riccio ME,Salamanca E,Meunier A,Henriot CP,Brossier CP,Bertrand X,Cooper BS,Harbarth S,Tacconelli E,Fluit AC,Rodriguez-Baño J,Kluytmans JAJW,Peter S,Hocquet D
Clin Microbiol Infect. 2021 Jul 26:S1198-743X(21)00414-6. doi: 10.1016/j.cmi.2021.07.022.
[Abstract] [PubMed]

New insights into pneumonia in patients on prolonged mechanical ventilation: need for a new paradigm addressing dysbiosis.
Rello J,Schrenzel J,Tejo AM
J Bras Pneumol. 2021 Jun 23;47(3):e20210198. doi: 10.36416/1806-3756/e20210198.
[Abstract] [PubMed]

12/111phiA Prophage Domestication Is Associated with Autoaggregation and Increased Ability to Produce Biofilm in Streptococcus agalactiae.
Renard A,Diene SM,Courtier-Martinez L,Gaillard JB,Gbaguidi-Haore H,Mereghetti L,Quentin R,Francois P,Van Der Mee-Marquet N
Microorganisms. 2021 May 21;9(6):1112. doi: 10.3390/microorganisms9061112.
[Abstract] [PubMed]

Performances of automated digital imaging of Gram-stained slides with on-screen reading against manual microscopy.
Fischer A,Azam N,Rasga L,Barras V,Tangomo M,Renzi G,Vuilleumier N,Schrenzel J,Cherkaoui A
Eur J Clin Microbiol Infect Dis. 2021 May 8. doi: 10.1007/s10096-021-04233-2.
[Abstract] [PubMed]

Distribution of pathogens and antimicrobial resistance in bacteraemia according to hospitalization duration: a nationwide surveillance study in Switzerland.
Buetti N,Marschall J,Timsit JF,Atkinson A,Kronenberg A,Sommerstein R
Clin Microbiol Infect. 2021 Apr 30:S1198-743X(21)00212-3. doi: 10.1016/j.cmi.2021.04.025.
[Abstract] [PubMed]

Temporal and regional incidence of carbapenemase-producing Enterobacterales, Switzerland, 2013 to 2018.
Ramette A,Gasser M,Nordmann P,Zbinden R,Schrenzel J,Perisa D,Kronenberg A
Euro Surveill. 2021 Apr;26(15):1900760. doi: 10.2807/1560-7917.ES.2021.26.15.1900760.
[Abstract] [PubMed]

Household acquisition and transmission of extended-spectrum β-lactamase (ESBL) -producing Enterobacteriaceae after hospital discharge of ESBL-positive index patients.
Riccio ME,Verschuuren T,Conzelmann N,Martak D,Meunier A,Salamanca E,Delgado M,Guther J,Peter S,Paganini J,Martischang R,Sauser J,de Kraker MEA,Cherkaoui A,Fluit AC,Cooper BS,Hocquet D,Kluytmans JAJW,Tacconelli E,Rodriguez-Baño J,Harbarth S
Clin Microbiol Infect. 2021 Jan 7:S1198-743X(20)30784-9. doi: 10.1016/j.cmi.2020.12.024.
[Abstract] [PubMed]

Case Report: About a Case of Hyperammonemia Syndrome Following Lung Transplantation: Could Metagenomic Next-Generation Sequencing Improve the Clinical Management?
Michel C,Raimo M,Lazarevic V,Gaïa N,Leduc N,Knoop C,Hallin M,Vandenberg O,Schrenzel J,Grimaldi D,Hites M
Front Med (Lausanne). 2021 Jul 6;8:684040. doi: 10.3389/fmed.2021.684040. eCollection 2021.
[Abstract] [PubMed]

Unexpectedly High False-Positive Rates for Haemophilus influenzae Using a Meningoencephalitis Syndromic PCR Panel in Two Tertiary Centers.
Zanella MC,Cherkaoui A,Hinic V,Renzi G,Goldenberger D,Egli A,Schrenzel J
Front Cell Infect Microbiol. 2021 Mar 8;11:639658. doi: 10.3389/fcimb.2021.639658. eCollection 2021.
[Abstract] [PubMed]

Oral Dysbiosis and Inflammation in Parkinson's Disease.
Fleury V,Zekeridou A,Lazarevic V,Gaïa N,Giannopoulou C,Genton L,Cancela J,Girard M,Goldstein R,Bally JF,Mombelli A,Schrenzel J,Burkhard PR
J Parkinsons Dis. 2021;11(2):619-631. doi: 10.3233/JPD-202459.
[Abstract] [PubMed]



Vertical and horizontal dissemination of an IncC plasmid harbouring rmtB 16S rRNA methylase gene, conferring resistance to plazomicin, among invasive ST258 and ST16 KPC-producing Klebsiella pneumoniae.
Roch M,Sierra R,Sands K,Martins WMBS,Schrenzel J,Walsh TR,Gales AC,Andrey DO
J Glob Antimicrob Resist. 2021 Mar;24:183-189. doi: 10.1016/j.jgar.2020.12.006. Epub 2020 Dec 26.
[Abstract] [PubMed]

Mapping of aetiologies of gastroenteritis: a systematic review and meta-analysis of pathogens identified using a multiplex screening array.
Meyer J,Roos E,Combescure C,Buchs NC,Frossard JL,Ris F,Toso C,Schrenzel J
Scand J Gastroenterol. 2020 Dec;55(12):1405-1410. doi: 10.1080/00365521.2020.1839128. Epub 2020 Nov 4.
[Abstract] [PubMed]

Respiratory tissue-associated commensal bacteria offer therapeutic potential against pneumococcal colonization.
Yildiz S,Pereira Bonifacio Lopes JP,Bergé M,González-Ruiz V,Baud D,Kloehn J,Boal-Carvalho I,Schaeren OP,Schotsaert M,Hathaway LJ,Rudaz S,Viollier PH,Hapfelmeier S,Francois P,Schmolke M
Elife. 2020 Dec 8;9:e53581. doi: 10.7554/eLife.53581.
[Abstract] [PubMed]

Influenza A viruses limit NLRP3-NEK7-complex formation and pyroptosis in human macrophages.
Boal-Carvalho I,Mazel-Sanchez B,Silva F,Garnier L,Yildiz S,Bonifacio JP,Niu C,Williams N,Francois P,Schwerk N,Schöning J,Carlens J,Viemann D,Hugues S,Schmolke M
EMBO Rep. 2020 Dec 3;21(12):e50421. doi: 10.15252/embr.202050421. Epub 2020 Nov 12.
[Abstract] [PubMed]

The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics.
Sancho-Vaello E,Gil-Carton D,François P,Bonetti EJ,Kreir M,Pothula KR,Kleinekathöfer U,Zeth K
Sci Rep. 2020 Oct 15;10(1):17356. doi: 10.1038/s41598-020-74401-5.
[Abstract] [PubMed]

Discordant Clostridioides difficile diagnostic assay and treatment practice: a cross-sectional study in a tertiary care hospital, Geneva, Switzerland.
Lenggenhager L,Zanella MC,Poncet A,Kaiser L,Schrenzel J
BMJ Open. 2020 Sep 13;10(9):e036342. doi: 10.1136/bmjopen-2019-036342.
[Abstract] [PubMed]

Messages from the Fourth International Conference on Clinical Metagenomics.
Charretier Y,Lazarevic V,Schrenzel J,Ruppé E
Microbes Infect. 2020 Nov-Dec;22(10):635-641. doi: 10.1016/j.micinf.2020.07.007. Epub 2020 Aug 20.
[Abstract] [PubMed]

Phylogeographical Analysis Reveals the Historic Origin, Emergence, and Evolutionary Dynamics of Methicillin-Resistant Staphylococcus aureus ST228.
Abdelbary MMH,Feil EJ,Senn L,Petignat C,Prod'hom G,Schrenzel J,François P,Werner G,Layer F,Strommenger B,Pantosti A,Monaco M,Denis O,Deplano A,Grundmann H,Blanc DS
Front Microbiol. 2020 Aug 26;11:2063. doi: 10.3389/fmicb.2020.02063. eCollection
[Abstract] [PubMed]

The GLP-1R agonist liraglutide limits hepatic lipotoxicity and inflammatory response in mice fed a methionine-choline deficient diet.
Somm E,Montandon SA,Loizides-Mangold U,Gaïa N,Lazarevic V,De Vito C,Perroud E,Bochaton-Piallat ML,Dibner C,Schrenzel J,Jornayvaz FR
Transl Res. 2021 Jan;227:75-88. doi: 10.1016/j.trsl.2020.07.008. Epub 2020 Jul 22.
[Abstract] [PubMed]

Population structure, genetic diversity and pathotypes of Streptococcus suis isolated during the last 13 years from diseased pigs in Switzerland.
Scherrer S,Rosato G,Spoerry Serrano N,Stevens MJA,Rademacher F,Schrenzel J,Gottschalk M,Stephan R,Peterhans S
Vet Res. 2020 Jul 8;51(1):85. doi: 10.1186/s13567-020-00813-w.
[Abstract] [PubMed]

Cutaneous ulcers revealing diphtheria: A re-emerging disease imported from Indian Ocean countries?
Alberto C,Osdoit S,Villani AP,Bellec L,Belmonte O,Schrenzel J,Bagny K,Badell E,Brisse S,Toubiana J
Ann Dermatol Venereol. 2021 Mar;148(1):34-39. doi: 10.1016/j.annder.2020.04.024. Epub 2020 Jul 3.
[Abstract] [PubMed]

Population structure, genetic diversity and pathotypes of Streptococcus suis isolated during the last 13 years from diseased pigs in Switzerland.
Scherrer S, Rosato G, Spoerry Serrano N, Stevens MJA, Rademacher F, Schrenzel J, Gottschalk M, Stephan R, Peterhans S
Vet Res. 2020 Jul 8;51(1):85. doi: 10.1186/s13567-020-00813-w.
[Abstract] [PubMed]

Impact of the Novel Prophage ?SA169 on Persistent Methicillin-Resistant Staphylococcus aureus Endovascular Infection.
Li L, Wang G, Li Y, Francois P, Bayer AS, Chen L, Seidl K, Cheung A, Xiong YQ
mSystems. 2020 Jun 30;5(3):e00178-20. doi: 10.1128/mSystems.00178-20.
[Abstract] [PubMed]

Digital microbiology.
Egli A, Schrenzel J, Greub G
Clin Microbiol Infect. 2020 Jun 27:S1198-743X(20)30367-0. doi: 10.1016/j.cmi.2020.06.023.
[Abstract] [PubMed]

Metagenomic Characterization of Gut Microbiota of Carriers of Extended-Spectrum Beta-Lactamase or Carbapenemase-Producing Enterobacteriaceae Following Treatment with Oral Antibiotics and Fecal Microbiota Transplantation: Results from a Multicenter Randomized Trial.
Leo S, Lazarevic V, Girard M, Gaïa N, Schrenzel J, de Lastours V, Fantin B, Bonten M, Carmeli Y, Rondinaud E, Harbarth S, Huttner BD
Microorganisms. 2020 Jun 23;8(6):E941. doi: 10.3390/microorganisms8060941.
[Abstract] [PubMed]

[Microbiota specificities among the elderly Summary of the 5th symposium « Feeding the Microbiota »].
Zanella MC, Genton L, Schrenzel J
Rev Med Suisse. 2020 Jun 17;16(698):1266-1269.
[Abstract] [PubMed]

SPHN/PHRT: Forming a Swiss-Wide Infrastructure for Data-Driven Sepsis Research.
Egli A, Battegay M, Büchler AC, Bühlmann P, Calandra T, Eckert P, Furrer H, Greub G, Jakob SM, Kaiser L, Leib SL, Marsch S, Meinshausen N, Pagani JL, Pugin J, Rätsch G, Schrenzel J, Schüpbach R, Siegemund M, Zamboni N, Zbinden R, Zinkernagel A, Borgwardt K
Stud Health Technol Inform. 2020 Jun 16;270:1163-1167. doi: 10.3233/SHTI200346.
[Abstract] [PubMed]

Strain coverage of Bexsero vaccine assessed by whole-genome sequencing over a cohort of invasive meningococci of serogroups B and W isolated in Switzerland.
Leo S, Lazarevic V, Girard M, Getaz-Jimenez Velasco GC, Gaïa N, Renzi G, Cherkaoui A, Hong E, Taha MK, Schrenzel J
Vaccine. 2020 Jul 14;38(33):5324-5331. doi: 10.1016/j.vaccine.2020.05.071. Epub 2020 Jun 16.
[Abstract] [PubMed]

Influenza-associated aspergillosis in critically-ill patients-a retrospective bicentric cohort study.
Waldeck F, Boroli F, Suh N, Wendel Garcia PD, Flury D, Notter J, Iten A, Kaiser L, Schrenzel J, Boggian K, Maggiorini M, Pugin J, Kleger GR, Albrich WC
Eur J Clin Microbiol Infect Dis. 2020 Jun 3:1-9. doi: 10.1007/s10096-020-03923-7.
[Abstract] [PubMed]

Septic shock caused by Capnocytophaga canis after a cat scratch.
Donner V, Buzzi M, Lazarevic V, Gaïa N, Girard M, Renzi F, Renzi G, Cherkaoui A, Schrenzel J
Eur J Clin Microbiol Infect Dis. 2020 May 24. doi: 10.1007/s10096-020-03922-8.
[Abstract] [PubMed]

Niche specialization and spread of Staphylococcus capitis involved in neonatal sepsis.
Wirth T, Bergot M, Rasigade JP, Pichon B, Barbier M, Martins-Simoes P, Jacob L, Pike R, Tissieres P, Picaud JC, Kearns A, Supply P, Butin M, Laurent F
Nat Microbiol. 2020 May;5(5):735-745. doi: 10.1038/s41564-020-0676-2. Epub 2020 Apr 27.
[Abstract] [PubMed]

Performances and usefulness of Xpert MTB/RIF assay in low-incidence settings: not that bad?
Pham TT, Schrenzel J, Janssens JP, Emonet S
Eur J Clin Microbiol Infect Dis. 2020 Apr 18. doi: 10.1007/s10096-020-03887-8.
[Abstract] [PubMed]

"French Phage Network" Annual Conference-Fifth Meeting Report.
Laumay F, Chaïb A, Linares R, Breyton C
Viruses. 2020 Apr 14;12(4):446. doi: 10.3390/v12040446.
[Abstract] [PubMed]

Implementation of the WASPLab™ and first year achievements within a university hospital.
Cherkaoui A, Renzi G, Viollet A, Fleischmann M, Metral-Boffod L, Dominguez-Amado D, Vuilleumier N, Schrenzel J
Eur J Clin Microbiol Infect Dis. 2020 Aug;39(8):1527-1534. doi: 10.1007/s10096-020-03872-1. Epub 2020 Apr 5.
[Abstract] [PubMed]

First case of Streptococcus suis infection in Switzerland: An emerging public health problem?
Olearo F, Marinosci A, Stephan R, Cherkaoui A, Renzi G, Gaia N, Leo S, Lazarevic V, Schrenzel J
Travel Med Infect Dis. 2020 Mar 5:101590. doi: 10.1016/j.tmaid.2020.101590.
[Abstract] [PubMed]

Rapid diagnostic tests for infectious diseases in the emergency department.
Bouzid D, Zanella MC, Kerneis S, Visseaux B, May L, Schrenzel J, Cattoir V
Clin Microbiol Infect. 2020 Feb 29:S1198-743X(20)30107-5. doi: 10.1016/j.cmi.2020.02.024.
[Abstract] [PubMed]

Changes in Microbiota Profiles After Prolonged Frozen Storage of Stool Suspensions.
Dorsaz S, Charretier Y, Girard M, Gaïa N, Leo S, Schrenzel J, Harbarth S, Huttner B, Lazarevic V
Front Cell Infect Microbiol. 2020 Feb 28;10:77. doi: 10.3389/fcimb.2020.00077. eCollection 2020.
[Abstract] [PubMed]

Second Periprosthetic Joint Infection Caused by Streptococcus dysgalactiae: How Genomic Sequencing Can Help Defining the Best Therapeutic Strategy.
Pham TT, Lazarevic V, Gaia N, Girard M, Cherkaoui A, Suva D, Schrenzel J
Front Med (Lausanne). 2020 Feb 21;7:53. doi: 10.3389/fmed.2020.00053. eCollection 2020.
[Abstract] [PubMed]

Rapid high resolution melting assay to differentiate Streptococcus suis serotypes 2, 1/2, 1, and 14.
Scherrer S, Rademacher F, Spoerry Serrano N, Schrenzel J, Gottschalk M, Stephan R, Landolt P
Microbiologyopen. 2020 Apr;9(4):e995. doi: 10.1002/mbo3.995. Epub 2020 Jan 22.
[Abstract] [PubMed]

Rapid identification by MALDI-TOF/MS and antimicrobial disk diffusion susceptibility testing for positive blood cultures after a short incubation on the WASPLab.
Cherkaoui A, Renzi G, Azam N, Schorderet D, Vuilleumier N, Schrenzel J
Eur J Clin Microbiol Infect Dis. 2020 Jun;39(6):1063-1070. doi: 10.1007/s10096-020-03817-8. Epub 2020 Jan 21.
[Abstract] [PubMed]

Comparative Transcriptomic and Functional Assessments of Linezolid-Responsive Small RNA Genes in Staphylococcus aureus.
Gao W, Guérillot R, Lin YH, Tree J, Beaume M, François P, Monk IR, Seemann T, Schrenzel J, Howden BP, Stinear TP
mSystems. 2020 Jan 7;5(1):e00665-19. doi: 10.1128/mSystems.00665-19.
[Abstract] [PubMed]

Comparison of the Copan WASPLab incorporating the BioRad expert system against the SIRscan 2000 automatic for routine antimicrobial disc diffusion susceptibility testing.
Cherkaoui A, Renzi G, Fischer A, Azam N, Schorderet D, Vuilleumier N, Schrenzel J
Clin Microbiol Infect. 2020 May;26(5):619-625. doi: 10.1016/j.cmi.2019.11.008. Epub 2019 Nov 13.
[Abstract] [PubMed]


Automated Incubation and Digital Image Analysis of Chromogenic Media Using Copan WASPLab Enables Rapid Detection of Vancomycin-Resistant Enterococcus.
Cherkaoui A, Renzi G, Charretier Y, Blanc DS, Vuilleumier N, Schrenzel J
Front Cell Infect Microbiol. 2019 Nov 6;9:379. doi: 10.3389/fcimb.2019.00379. eCollection 2019.
[Abstract] [PubMed]

Comparative Genome Analysis of Staphylococcus lugdunensis Shows Clonal Complex-Dependent Diversity of the Putative Virulence Factor, ess/Type VII Locus.
Lebeurre J, Dahyot S, Diene S, Paulay A, Aubourg M, Argemi X, Giard JC, Tournier I, François P, Pestel-Caron M
Front Microbiol. 2019 Oct 31;10:2479. doi: 10.3389/fmicb.2019.02479. eCollection 2019.
[Abstract] [PubMed]

Atypical presentation of Lemierre's syndrome: case report and literature review.
Laurencet ME, Rosset-Zufferey S, Schrenzel J
BMC Infect Dis. 2019 Oct 21;19(1):868. doi: 10.1186/s12879-019-4538-6.
[Abstract] [PubMed]

Disrupting Myelin-Specific Th17 Cell Gut Homing Confers Protection in an Adoptive Transfer Experimental Autoimmune Encephalomyelitis.
Duc D, Vigne S, Bernier-Latmani J, Yersin Y, Ruiz F, Gaïa N, Leo S, Lazarevic V, Schrenzel J, Petrova TV, Pot C
Cell Rep. 2019 Oct 8;29(2):378-390.e4. doi: 10.1016/j.celrep.2019.09.002.
[Abstract] [PubMed]

From genotype to antibiotic susceptibility phenotype in the order Enterobacterales: a clinical perspective.
Ruppé E, Cherkaoui A, Charretier Y, Girard M, Schicklin S, Lazarevic V, Schrenzel J
Clin Microbiol Infect. 2020 May;26(5):643.e1-643.e7. doi: 10.1016/j.cmi.2019.09.018. Epub 2019 Oct 3.
[Abstract] [PubMed]

Next-Generation Sequencing for the Diagnosis of Challenging Culture-Negative Endocarditis.
Kolb M, Lazarevic V, Emonet S, Calmy A, Girard M, Gaïa N, Charretier Y, Cherkaoui A, Keller P, Huber C, Schrenzel J
Front Med (Lausanne). 2019 Sep 20;6:203. doi: 10.3389/fmed.2019.00203. eCollection 2019.
[Abstract] [PubMed]

Targeting the Gut Microbiota to Treat Cachexia.
Genton L, Mareschal J, Charretier Y, Lazarevic V, Bindels LB, Schrenzel J
Front Cell Infect Microbiol. 2019 Sep 12;9:305. doi: 10.3389/fcimb.2019.00305. eCollection 2019.
[Abstract] [PubMed]

Symposium report: One Health meets sequencing.
Egli A, Koch D, Danuser J, Hendriksen RS, Driesen S, Schmid DC, Neher R, Mäusezahl M, Seth-Smith HMB, Bloemberg G, Tschudin-Sutter S, Endimiani A, Perreten V, Greub G, Schrenzel J, Stephan R
Microbes Infect. 2020 Jan-Feb;22(1):1-7. doi: 10.1016/j.micinf.2019.07.004. Epub 2019 Aug 8.
[Abstract] [PubMed]

Rare Case of Community-Acquired Endocarditis Caused by Neisseria meningitidis Assessed by Clinical Metagenomics.
Choutko V, Lazarevic V, Gaïa N, Girard M, Renzi G, Leo S, Keller PM, Huber C, Schrenzel J
Front Cardiovasc Med. 2019 Aug 6;6:112. doi: 10.3389/fcvm.2019.00112. eCollection 2019.
[Abstract] [PubMed]

Identification of respiratory microbiota markers in ventilator-associated pneumonia.
Emonet S, Lazarevic V, Leemann Refondini C, Gaïa N, Leo S, Girard M, Nocquet Boyer V, Wozniak H, Després L, Renzi G, Mostaguir K, Dupuis Lozeron E, Schrenzel J, Pugin J
Intensive Care Med. 2019 Aug;45(8):1082-1092. doi: 10.1007/s00134-019-05660-8. Epub 2019 Jun 17.
[Abstract] [PubMed]

A molecular based diagnosis of positive blood culture in the context of viral haemorrhagic fever: proof of concept.
Cherkaoui A, Cherpillod P, Renzi G, Schrenzel J, Kaiser L, Schibler M
Clin Microbiol Infect. 2019 Oct;25(10):1289.e1-1289.e4. doi: 10.1016/j.cmi.2019.05.021. Epub 2019 Jun 6.
[Abstract] [PubMed]

Estimating the association between antibiotic exposure and colonization with extended-spectrum β-lactamase-producing Gram-negative bacteria using machine learning methods: a multicentre, prospective cohort study.
Tacconelli E, Górska A, De Angelis G, Lammens C, Restuccia G, Schrenzel J, Huson DH, Carevic B, Preotescu L, Carmeli Y, Kazma M, Spanu T, Carrara E, Malhotra-Kumar S, Gladstone BP
Clin Microbiol Infect. 2020 Jan;26(1):87-94. doi: 10.1016/j.cmi.2019.05.013. Epub 2019 May 23.
[Abstract] [PubMed]

Genomic epidemiology of Neisseria meningitidis serogroup W in Switzerland between 2010 and 2016.
Leo S, Lazarevic V, Girard M, Velasco GCG, Anson L, Gaïa N, Renzi G, Cherkaoui A, Born R, Basler S, Schrenzel J
J Infect. 2019 Sep;79(3):277-287. doi: 10.1016/j.jinf.2019.05.014. Epub 2019 May 21.
[Abstract] [PubMed]

[Fecal microbiota transplantation : current status and prospects].
Gilbert B, Schrenzel J
Rev Med Suisse. 2019 May 8;15(650):976-983.
[Abstract] [PubMed]

Listeria monocytogenes infectious periaortitis: a case report from the infectious disease standpoint.
Foulex A, Coen M, Cherkaoui A, Lazarevic V, Gaïa N, Leo S, Girard M, Mugnai D, Schrenzel J
BMC Infect Dis. 2019 Apr 16;19(1):326. doi: 10.1186/s12879-019-3953-z.
[Abstract] [PubMed]

Copan WASPLab automation significantly reduces incubation times and allows earlier culture readings.
Cherkaoui A, Renzi G, Vuilleumier N, Schrenzel J
Clin Microbiol Infect. 2019 Nov;25(11):1430.e5-1430.e12. doi: 10.1016/j.cmi.2019.04.001. Epub 2019 Apr 12.
[Abstract] [PubMed]

Microbiological diagnostics of bloodstream infections in Europe-an ESGBIES survey.
Idelevich EA, Seifert H, Sundqvist M, Scudeller L, Amit S, Balode A, Bilozor A, Drevinek P, Kocak Tufan Z, Koraqi A, Lamy B, Marekovic I, Miciuleviciene J, Müller Premru M, Pascual A, Pournaras S, Saegeman V, Schønheyder HC, Schrenzel J, Strateva T, Tilley R, Wiersinga WJ, Zabicka D, Carmeli Y, Becker K
Clin Microbiol Infect. 2019 Nov;25(11):1399-1407. doi: 10.1016/j.cmi.2019.03.024. Epub 2019 Apr 10.
[Abstract] [PubMed]

[Diphtheria: new clinical presentations of an old disease].
Coen M, Alberto C, Éperon G, Cherkaoui A, Schrenzel J
Rev Med Suisse. 2019 Apr 10;15(646):786-790.
[Abstract] [PubMed]

The Polycyclic Polyprenylated Acylphloroglucinol Antibiotic PPAP 23 Targets the Membrane and Iron Metabolism in Staphylococcus aureus.
Wang H, Kraus F, Popella P, Baykal A, Guttroff C, François P, Sass P, Plietker B, Götz F.
Front Microbiol. 2019 Jan 22;10:14. doi: 10.3389/fmicb.2019.00014. eCollection 2019.
[Abstract] [PubMed]

Temperate Prophages Increase Bacterial Adhesin Expression and Virulence in an Experimental Model of Endocarditis Due to Staphylococcus aureus From the CC398 Lineage.
Laumay F, Corvaglia AR, Diene SM, Girard M, Oechslin F, van der Mee-Marquet N, Entenza JM, François P.
Front Microbiol. 2019 Apr 24;10:742. doi: 10.3389/fmicb.2019.00742. eCollection 2019.
[Abstract] [PubMed]

Prevalence and characterization of Staphylococcus aureus in wastewater treatment plants by whole genomic sequencing.
Amirsoleimani A, Brion GM, Diene SM, François P, Richard EM.
Water Res. 2019 Jul 1;158:193-202. doi: 10.1016/j.watres.2019.04.035. Epub 2019 Apr 15.
[Abstract] [PubMed]

fbl-Typing of Staphylococcus lugdunensis: A Frontline Tool for Epidemiological Studies, but Not Predictive of Fibrinogen Binding Ability.
Dahyot S, Lebeurre J, Laumay F, Argemi X, Dubos C, Lemée L, Prévost G, François P, Pestel-Caron M.
Front Microbiol. 2019 May 17;10:1109. doi: 10.3389/fmicb.2019.01109. eCollection 2019.
[Abstract] [PubMed]

Inactivation of farR Causes High Rhodomyrtone Resistance and Increased Pathogenicity in Staphylococcus aureus.
Nguyen MT, Saising J, Tribelli PM, Nega M, Diene SM, François P, Schrenzel J, Spröer C, Bunk B, Ebner P, Hertlein T, Kumari N, Härtner T, Wistuba D, Voravuthikunchai SP, Mäder U, Ohlsen K, Götz F.
Front Microbiol. 2019 May 28;10:1157. doi: 10.3389/fmicb.2019.01157. eCollection 2019.
[Abstract] [PubMed]

A multifaceted small RNA modulates gene expression upon glucose limitation in Staphylococcus aureus.
Bronesky D, Desgranges E, Corvaglia A, François P, Caballero CJ, Prado L, Toledo-Arana A, Lasa I, Moreau K, Vandenesch F, Marzi S, Romby P, Caldelari I.
EMBO J. 2019 Mar 15;38(6). pii: e99363. doi: 10.15252/embj.201899363. Epub 2019 Feb 13.
[Abstract] [PubMed]

Messages from the third International Conference on Clinical Metagenomics (ICCMg3).
Ruppé E, Schrenzel J.
Microbes Infect. 2019 Mar 2. pii: S1286-4579(19)30026-7. doi: 10.1016/j.micinf.2019.02.004. [Epub ahead of print]
[Abstract] [PubMed]

Potential in vivo transfer of a blaCTX-M14-harbouring plasmid established by combining long- and short-read sequencing.
Xavier BB, Renzi G, Lammens C, Cherkaoui A, Goossens H, Schrenzel J, Harbarth S, Malhotra-Kumar S.
J Microbiol Methods. 2019 Feb 7. pii: S0167-7012(18)30789-9. doi: 10.1016/j.mimet.2019.02.004. [Epub ahead of print]
[Abstract] [PubMed]

The intestinal microbiota predisposes to traveler's diarrhea and to the carriage of multidrug-resistant Enterobacteriaceae after traveling to tropical regions.
Leo S, Lazarevic V, Gaïa N, Estellat C, Girard M, Matheron S, Armand-Lefèvre L, Andremont A The VOYAG-R study group, Schrenzel J, Ruppé E.
Gut Microbes. 2019 Feb 3:1-11. doi: 10.1080/19490976.2018.1564431. [Epub ahead of print]
[Abstract] [PubMed]

Comparison of analytical performances of the Roche Cobas 6800 CT/NG assay with the Abbott m2000 Real Time CT/NG assay for detecting Chlamydia trachomatis and Neisseria gonorrhoeae.
Cherkaoui A, Renzi G, Mombelli M, Jaton K, Yerly S, Vuilleumier N, Schrenzel J.
J Med Microbiol. 2019 Feb;68(2):197-200. doi: 10.1099/jmm.0.000909. Epub 2019 Jan 3.
[Abstract] [PubMed]

Massive Diversity in Whole-Genome Sequences of Streptococcus suis Strains from Infected Pigs in Switzerland.
Stevens MJA, Spoerry Serrano N, Cernela N, Schmitt S, Schrenzel J, Stephan R.
Microbiol Resour Announc. 2019 Jan 31;8(5). pii: e01656-18. doi: 10.1128/MRA.01656-18. eCollection 2019 Jan.
[Abstract] [PubMed]

High-throughput sequencing for the aetiologic identification of viral encephalitis, meningoencephalitis, and meningitis. A narrative review and clinical appraisal.
Zanella MC, Lenggenhager L, Schrenzel J, Cordey S, Kaiser L.
Clin Microbiol Infect. 2019 Jan 11. pii: S1198-743X(18)30812-7. doi: 10.1016/j.cmi.2018.12.022. [Epub ahead of print] Review.
[Abstract] [PubMed]

Antibiotics Stimulate Formation of Vesicles in Staphylococcus aureus in both Phage-Dependent and -Independent Fashions and via Different Routes.
Andreoni F, Toyofuku M, Menzi C, Kalawong R, Mairpady Shambat S, François P, Zinkernagel AS, Eberl L.
Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01439-18. doi: 10.1128/AAC.01439-18. Print 2019 Feb.
[Abstract] [PubMed]

YpdA, a putative bacillithiol disulfide reductase, contributes to cellular redox homeostasis and virulence in Staphylococcus aureus.
Mikheyeva IV, Thomas JM, Kolar SL, Corvaglia AR, Gaïa N, Leo S, Francois P, Liu GY, Rawat M, Cheung AL.
Mol Microbiol. 2019 Jan 12. doi: 10.1111/mmi.14207. [Epub ahead of print]
[Abstract] [PubMed]

Response to the letter to the editor: Comment on "Streptococcus anginosus Dental Implant-Related Osteomyelitis of the Jaws: An Insidious and Calamitous Entity".
Scolozzi P, Chatelain S, Schrenzel J, Lombardi T.
J Oral Maxillofac Surg. 2019 Jan;77(1):4. doi: 10.1016/j.joms.2018.09.005. Epub 2018 Oct 16. No abstract available.
[Abstract] [PubMed]



Differential daptomycin resistance development in Staphylococcus aureus strains with active and mutated gra regulatory systems.
Müller A, Grein F, Otto A, Gries K, Orlov D, Zarubaev V, Girard M, Sher X, Shamova O, Roemer T, François P, Becher D, Schneider T, Sahl HG.
Int J Med Microbiol. 2018 Apr;308(3):335-348. doi: 10.1016/j.ijmm.2017.12.002. Epub 2017 Dec 21.
[Abstract] [PubMed]

Catheter-related infections: does the spectrum of microbial causes change over time? A nationwide surveillance study.
Buetti N, Lo Priore E, Atkinson A, Widmer AF, Kronenberg A, Marschall J; Swiss Centre for Antibiotic Resistance (ANRESIS).
BMJ Open. 2018 Dec 22;8(12):e023824. doi: 10.1136/bmjopen-2018-023824.
[Abstract] [PubMed]

Improving the quality and workflow of bacterial genome sequencing and analysis: paving the way for a Switzerland-wide molecular epidemiological surveillance platform.
Egli A, Blanc DS, Greub G, Keller PM, Lazarevic V, Lebrand A, Leib S, Neher RA, Perreten V, Ramette A, Schrenzel J, Stephan R, Wagner K, Wuethrich D, Xenarios I.
Swiss Med Wkly. 2018 Dec 15;148:w14693. doi: 10.4414/smw.2018.14693. eCollection 2018 Dec 3.
[Abstract] [PubMed]

A community outbreak of Legionnaires' disease in Geneva, Switzerland, June to September 2017.
Zanella MC, Yerly S, CherkaouiI A, Renzi G, Mamin A, Lourenço Cordes L, Delaporte E, Baranczuk-Turska Z, Keiser O, Schrenzel J, Harbarth S, Gaia V, Kaiser L.
Swiss Med Wkly. 2018 Dec 2;148:w14687. doi: 10.4414/smw.2018.14687. eCollection 2018 Nov 19.
[Abstract] [PubMed]

A comparison of Sensititre™ Anaerobe MIC plate with ATB ANA® test for the routine susceptibility testing of common anaerobe pathogens.
Cherkaoui A, Fischer A, Azam N, Riat A, Schrenzel J.
Eur J Clin Microbiol Infect Dis. 2018 Dec;37(12):2279-2284. doi: 10.1007/s10096-018-3369-5. Epub 2018 Sep 6.
[Abstract] [PubMed]

Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements.
Fabbiano S, Suárez-Zamorano N, Chevalier C, Lazarevic V, Kieser S, Rigo D, Leo S, Veyrat-Durebex C, Gaïa N, Maresca M, Merkler D, Gomez de Agüero M, Macpherson A, Schrenzel J, Trajkovski M.
Cell Metab. 2018 Dec 4;28(6):907-921.e7. doi: 10.1016/j.cmet.2018.08.005. Epub 2018 Aug 30.
[Abstract] [PubMed]

Molecular characterization of fluoroquinolones, macrolides, and imipenem resistance in Haemophilus influenzae: analysis of the mutations in QRDRs and assessment of the extent of the AcrAB-TolC-mediated resistance.
Cherkaoui A, Gaïa N, Baud D, Leo S, Fischer A, Ruppe E, François P, Schrenzel J.
Eur J Clin Microbiol Infect Dis. 2018 Nov;37(11):2201-2210. doi: 10.1007/s10096-018-3362-z. Epub 2018 Aug 25.
[Abstract] [PubMed]

Emergence of ESBL-producing Escherichia coli ST131-C1-M27 clade colonizing patients in Europe.
Merino I, Hernández-García M, Turrientes MC, Pérez-Viso B, López-Fresneña N, Diaz-Agero C, Maechler F, Fankhauser-Rodriguez C, Kola A, Schrenzel J, Harbarth S, Bonten M, Gastmeier P, Canton R, Ruiz-Garbajosa P; R-GNOSIS Study Group .
J Antimicrob Chemother. 2018 Nov 1;73(11):2973-2980. doi: 10.1093/jac/dky296.
[Abstract] [PubMed]

[Current status of probiotics usage for the prevention of a first episode of Clostridium difficile infection].
Cantero C, Schrenzel J, Darbellay Farhoumand P.
Rev Med Suisse. 2018 Oct 17;14(623):1834-1837. French.
[Abstract] [PubMed]

Root Microbiota in Primary and Secondary Apical Periodontitis.
Bouillaguet S, Manoil D, Girard M, Louis J, Gaïa N, Leo S, Schrenzel J, Lazarevic V.
Front Microbiol. 2018 Oct 9;9:2374. doi: 10.3389/fmicb.2018.02374. eCollection 2018.
[Abstract] [PubMed]

Epidemiology of subsequent bloodstream infections in the ICU.
Buetti N, Lo Priore E, Sommerstein R, Atkinson A, Kronenberg A, Marschall J; Swiss Centre for Antibiotic resistance (ANRESIS).
Crit Care. 2018 Oct 11;22(1):259. doi: 10.1186/s13054-018-2148-0.
[Abstract] [PubMed]

[Meningococcal infections in Switzerland : changes in epidemiology, clinical manifestations and prophylaxis].
Emonet S, Born R, Schrenzel J.
Rev Med Suisse. 2018 Oct 10;14(622):1781-1784. French.
[Abstract] [PubMed]

Fecal microbiota transplantation: a promising strategy in preventing the progression of non-alcoholic steatohepatitis and improving the anti-cancer immune response.
Delaune V, Orci LA, Lacotte S, Peloso A, Schrenzel J, Lazarevic V, Toso C.
Expert Opin Biol Ther. 2018 Oct;18(10):1061-1071. doi: 10.1080/14712598.2018.1518424. Epub 2018 Sep 10.
[Abstract] [PubMed]

Multiple-Locus Variable Number Tandem Repeat Analysis (MLVA) and Tandem Repeat Sequence Typing (TRST), helpful tools for subtyping Staphylococcus lugdunensis.
Dahyot S, Lebeurre J, Argemi X, François P, Lemée L, Prévost G, Pestel-Caron M.
Sci Rep. 2018 Aug 3;8(1):11669. doi: 10.1038/s41598-018-30144-y.
[Abstract] [PubMed]

Remarkable geographical variations between India and Europe in carriage of the staphylococcal surface protein-encoding sasX/sesI and in the population structure of methicillin-resistant Staphylococcus aureus belonging to clonal complex 8.
De Backer S, Xavier BB, Vanjari L, Coppens J, Lammens C, Vemu L, Carevic B, Hryniewicz W, Jorens P, Kumar-Singh S, Lee A, Harbarth S, Schrenzel J, Tacconelli E, Goossens H, Malhotra-Kumar S.
Clin Microbiol Infect. 2018 Aug 2. pii: S1198-743X(18)30542-1. doi: 10.1016/j.cmi.2018.07.024. [Epub ahead of print]
[Abstract] [PubMed]

Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus.
Reichert S, Ebner P, Bonetti EJ, Luqman A, Nega M, Schrenzel J, Spröer C, Bunk B, Overmann J, Sass P, François P, Götz F.
Front Microbiol. 2018 Jul 12;9:1539. doi: 10.3389/fmicb.2018.01539. eCollection 2018.
[Abstract] [PubMed]

When Bacterial Culture Fails, Metagenomics Can Help: A Case of Chronic Hepatic Brucelloma Assessed by Next-Generation Sequencing.
Lazarevic V, Gaïa N, Girard M, Leo S, Cherkaoui A, Renzi G, Emonet S, Jamme S, Ruppé E, Vijgen S, Rubbia-Brandt L, Toso C, Schrenzel J.
Front Microbiol. 2018 Jul 17;9:1566. doi: 10.3389/fmicb.2018.01566. eCollection 2018.
[Abstract] [PubMed]

Colistin heteroresistance and the involvement of the PmrAB regulatory system in Acinetobacter baumannii.
Charretier Y, Diene SM, Baud D, Chatellier S, Santiago-Allexant E, van Belkum A, Guigon G, Schrenzel J.
Antimicrob Agents Chemother. 2018 Jun 18. pii: AAC.00788-18. doi: 10.1128/AAC.00788-18. [Epub ahead of print]
[Abstract] [PubMed]

Accuracy of Sensititre YeastOne echinocandins epidemiological cut-off values for identification of FKS mutant Candida albicans and Candida glabrata: a ten year national survey of the Fungal Infection Network of Switzerland (FUNGINOS).
Kritikos A, Neofytos D, Khanna N, Schreiber PW, Boggian K, Bille J, Schrenzel J, Mühlethaler K, Zbinden R, Bruderer T, Goldenberger D, Pfyffer G, Conen A, Van Delden C, Zimmerli S, Sanglard D, Bachmann D, Marchetti O, Lamoth F; Fungal Infection Network of Switzerland (FUNGINOS).
Clin Microbiol Infect. 2018 Jun 15. pii: S1198-743X(18)30445-2. doi: 10.1016/j.cmi.2018.05.012. [Epub ahead of print]
[Abstract] [PubMed]

[Microbiota and malnutrition: an overview].
Mareschal J, Schrenzel J, Lazarevic V, Genton L.
Rev Med Suisse. 2018 Jun 6;14(610):1194-1199. French.
[Abstract] [PubMed]

Fast identification of dermatophytes by MALDI-TOF/MS using direct transfer of fungal cells on ground steel target plates.
da Cunha KC, Riat A, Normand AC, Bosshard PP, de Almeida MTG, Piarroux R, Schrenzel J, Fontao L.
Mycoses. 2018 May 15. doi: 10.1111/myc.12793. [Epub ahead of print]
[Abstract] [PubMed]

Differential expression of hemoglobin receptor, HmbR, between carriage and invasive isolates of Neisseria meningitidis contributes to virulence: lessons from a clonal outbreak.
Sevestre J, Diene SM, Aouiti-Trabelsi M, Deghmane AE, Tournier I, François P, Caron F, Taha MK.
Virulence. 2018 Apr 11:1-18. doi: 10.1080/21505594.2018.1460064. [Epub ahead of print]
[Abstract] [PubMed]

Fluconazole non-susceptible breakthrough candidemia after prolonged low-dose prophylaxis: a prospective FUNGINOS study.
Orasch C, Mertz D, Garbino J, van Delden C, Emonet S, Schrenzel J, Zimmerli S, Damonti L, Mühlethaler K, Imhof A, Ruef C, Fehr J, Zbinden R, Boggian K, Bruderer T, Flückiger U, Conen A, Khanna N, Frei R, Bregenzer T, Lamoth F, Erard V, Bochud PY, Calandra T, Bille J, Marchetti O; Fungal Infection Network of Switzerland (FUNGINOS).
J Infect. 2018 Jan 31. pii: S0163-4453(18)30029-X. doi: 10.1016/j.jinf.2017.12.018. [Epub ahead of print]
[Abstract] [PubMed]

Azole resistance of Aspergillus fumigatus isolates from the environment and the clinic in Switzerland.
Riat A, Plojoux J, Gindro K, Schrenzel J, Sanglard D.
Antimicrob Agents Chemother. 2018 Feb 5. pii: AAC.02088-17. doi: 10.1128/AAC.02088-17. [Epub ahead of print]
[Abstract] [PubMed]

Control of Infectious Diseases in the Era of European Clinical Microbiology Laboratory Consolidation: New Challenges and Opportunities for the Patient and for Public Health Surveillance.
Vandenberg O, Kozlakidis Z, Schrenzel J, Struelens MJ, Breuer J.
Front Med (Lausanne). 2018 Feb 2;5:15. doi: 10.3389/fmed.2018.00015. eCollection 2018.
[Abstract] [PubMed]

Messages from the second International Conference on Clinical Metagenomics (ICCMg2).
Ruppé E, Schrenzel J.
Microbes Infect. 2018 Mar 7. pii: S1286-4579(18)30049-2. doi: 10.1016/j.micinf.2018.02.005. [Epub ahead of print]
[Abstract] [PubMed]

Transcriptional Modulation of Penicillin-Binding Protein 1b, Outer Membrane Protein P2 and Efflux Pump (AcrAB-TolC) during Heat Stress Is Correlated to Enhanced Bactericidal Action of Imipenem on Non-typeable Haemophilus influenzae.
Cherkaoui A, Diene SM, Fischer A, Leo S, François P, Schrenzel J.
Front Microbiol. 2018 Jan 12;8:2676. doi: 10.3389/fmicb.2017.02676. eCollection 2017.
[Abstract] [PubMed]

A Potential New Human Pathogen Belonging to Helicobacter Genus, Identified in a Bloodstream Infection.
van der Mee-Marquet NL, Bénéjat L, Diene SM, Lemaignen A, Gaïa N, Smet A, Haesebrouck F, Cherkaoui A, Ducournau A, Lacomme S, Gontier E, Bernard L, Mégraud F, Goudeau A, Lehours P, François P.
Front Microbiol. 2017 Dec 18;8:2533. doi: 10.3389/fmicb.2017.02533. eCollection 2017.
[Abstract] [PubMed]


Management and investigation of a Serratia marcescens outbreak in a neonatal unit in Switzerland - the role of hand hygiene and whole genome sequencing - R1, ARIC-D-17-00143.
Zingg W, Soulake I, Baud D, Huttner B, Pfister R, Renzi G, Pittet D, Schrenzel J, Francois P.
Antimicrob Resist Infect Control. 2017 Dec 11;6:125. doi: 10.1186/s13756-017-0285-x. eCollection 2017.
[Abstract] [PubMed]

In vivo selection of a multidrug-resistant Aeromonas salmonicida during medicinal leech therapy.
Ruppé E, Cherkaoui A, Wagner N, La Scala GC, Beaulieu JY, Girard M, Frey J, Lazarevic V, Schrenzel J.
New Microbes New Infect. 2017 Oct 10;21:23-27. doi: 10.1016/j.nmni.2017.10.005. eCollection 2018 Jan.
[Abstract] [PubMed]

Establishing Genotype-to-Phenotype Relationships in Bacteria Causing Hospital-Acquired Pneumonia: A Prelude to the Application of Clinical Metagenomics.
Ruppé E, Cherkaoui A, Lazarevic V, Emonet S, Schrenzel J.
Antibiotics (Basel). 2017 Nov 29;6(4). pii: E30. doi: 10.3390/antibiotics6040030. Review.
[Abstract] [PubMed]

The Swiss Society of Microbiology: Small Bugs, Big Questions and Cool Answers.
Greub G, Holliger C, Sanglard D, Schrenzel J, Thiel V, Viollier P.
Chimia (Aarau). 2016 Dec 21;70(12):874-877. doi: 10.2533/chimia.2016.874.
[Abstract] [PubMed]

Draft Genome Sequence of Kingella negevensis SW7208426, the First European Strain of K. negevensis Isolated from a Healthy Child in Switzerland.
El Houmami N, Schrenzel J, Yagupsky P, Robert C, Ceroni D, Raoult D, Fournier PE.
Genome Announc. 2017 Jun 29;5(26). pii: e00571-17. doi: 10.1128/genomeA.00571-17.
[Abstract] [PubMed]

Acute Septic Arthritis of the Knee Caused by Kingella kingae in a 5-Year-Old Cameroonian Boy.
El Houmami N, Ceroni D, Codjo Seignon K, Pons JC, Lambert C, Durand GA, Minodier P, Lamah L, Bidet P, Schrenzel J, Raoult D, Fournier PE.
Front Pediatr. 2017 Nov 6;5:230. doi: 10.3389/fped.2017.00230. eCollection 2017.
[Abstract] [PubMed]

Structural remodeling and oligomerization of human cathelicidin on membranes suggest fibril-like structures as active species.
Sancho-Vaello E, François P, Bonetti EJ, Lilie H, Finger S, Gil-Ortiz F, Gil-Carton D, Zeth K.
Sci Rep. 2017 Nov 13;7(1):15371. doi: 10.1038/s41598-017-14206-1.
[Abstract] [PubMed]

A Novel Mechanism of Inactivating Antibacterial Nitro Compounds in the Human Pathogen Staphylococcus aureus by Overexpression of a NADH-dependent Flavin Nitroreductase.
El-Hossary EM, Förstner KU, François P, Baud D, Streker K, Schrenzel J, Ohlsen K, Holzgrabe U.
Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01510-17. doi: 10.1128/AAC.01510-17. [Epub ahead of print]
[Abstract] [PubMed]

Small RNA Teg49 is derived from a sarA transcript and regulates virulence genes independent of SarA in Staphylococcus aureus.
Manna AC, Kim S, Cengher L, Corvaglia A, Leo S, Francois P, Cheung AL.
Infect Immun. 2017 Nov 13. pii: IAI.00635-17. doi: 10.1128/IAI.00635-17. [Epub ahead of print]
[Abstract] [PubMed]

A transversal pilot study of oropharyngeal carriage of Kingella kingae in healthy children younger than 6 months.
Spyropoulou V, Brändle G, Maggio ABR, Anderson Della Llana R, Cherkaoui A, Renzi G, Schrenzel J, Manzano S, Ceroni D.
World J Pediatr. 2017 Dec;13(6):615-617. doi: 10.1007/s12519-017-0060-3. Epub 2017 Oct 20.
[Abstract] [PubMed]

Detection of Bacterial Pathogens from Broncho-Alveolar Lavage by Next-Generation Sequencing.
Leo S, Gaïa N, Ruppé E, Emonet S, Girard M, Lazarevic V, Schrenzel J.
Int J Mol Sci. 2017 Sep 20;18(9). pii: E2011. doi: 10.3390/ijms18092011.
[Abstract] [PubMed]

Association between oropharyngeal carriage of Kingella kingae and osteoarticular infection in young children: a case-control study.
Gravel J, Ceroni D, Lacroix L, Renaud C, Grimard G, Samara E, Cherkaoui A, Renzi G, Schrenzel J, Manzano S.
CMAJ. 2017 Sep 5;189(35):E1107-E1111. doi: 10.1503/cmaj.170127.
[Abstract] [PubMed]

Clinical metagenomics of bone and joint infections: a proof of concept study.
Ruppé E, Lazarevic V, Girard M, Mouton W, Ferry T, Laurent F, Schrenzel J.
Sci Rep. 2017 Aug 10;7(1):7718. doi: 10.1038/s41598-017-07546-5.
[Abstract] [PubMed]

[How to use microbiological diagnostic tests in a hospital setting].
Martischang R, Abbas M, Harbarth S, Huttner B, Schrenzel J.
Rev Med Suisse. 2017 Apr 12;13(558):792-796. French.
[Abstract] [PubMed]

Analysis of the prophages carried by human infecting isolates provides new insight into the evolution of Group B Streptococcus species.
van der Mee-Marquet N, Diene SM, Barbera L, Courtier-Martinez L, Lafont L, Ouachée A, Valentin AS, Santos SD, Quentin R, François P; Regional Group of infection control of the Centre Val de Loire region.
Clin Microbiol Infect. 2017 Sep 1. pii: S1198-743X(17)30483-4. doi: 10.1016/j.cmi.2017.08.024. [Epub ahead of print]
[Abstract] [PubMed]

Impact of exposure of methicillin-resistant Staphylococcus aureus to polyhexanide in vitro and in vivo.
Renzoni A, Von Dach E, Landelle C, Diene SM, Manzano C, Gonzales R, Abdelhady W, Randall CP, Bonetti EJ, Baud D, O'Neill AJ, Bayer A, Cherkaoui A, Schrenzel J, Harbarth S, François P.
Antimicrob Agents Chemother. 2017 Aug 7. pii: AAC.00272-17. doi: 10.1128/AAC.00272-17. [Epub ahead of print]
[Abstract] [PubMed]

Isolation and characterization of Kingella negevensis sp. nov., a novel Kingella species detected in a healthy paediatric population.
Houmami NE, Bakour S, Bzdrenga J, Rathored J, Seligmann H, Robert C, Armstrong N, Schrenzel J, Raoult D, Yagupsky P, Fournier PE.
Int J Syst Evol Microbiol. 2017 Jul 12. doi: 10.1099/ijsem.0.001957. [Epub ahead of print]
[Abstract] [PubMed]

Clinical Metagenomics for the Diagnostic of Hospital-acquired Infections: Promises and Hurdles.
Emonet S, Lazarevic V, Pugin J, Schrenzel J, Ruppé E.
Am J Respir Crit Care Med. 2017 Jul 5. doi: 10.1164/rccm.201705-0983LE. [Epub ahead of print] No abstract available.
[PubMed]

Draft Genome Sequence of Kingella negevensis SW7208426, the First European Strain of K. negevensis Isolated from a Healthy Child in Switzerland.
El Houmami N, Schrenzel J, Yagupsky P, Robert C, Ceroni D, Raoult D, Fournier PE.
Genome Announc. 2017 Jun 29;5(26). pii: e00571-17. doi: 10.1128/genomeA.00571-17.
[Abstract] [PubMed]

The Swiss Society of Microbiology: Small Bugs, Big Questions and Cool Answers.
Greub G, Holliger C, Sanglard D, Schrenzel J, Thiel V, Viollier P.
Chimia (Aarau). 2016 Dec 21;70(12):874-877. doi: 10.2533/chimia.2016.874.
[Abstract] [PubMed]

Rapid identification of ST131 Escherichia coli by a novel multiplex real-time allelic discrimination assay.
François P, Bonetti EJ, Fankhauser C, Baud D, Cherkaoui A, Schrenzel J, Harbarth S.
J Microbiol Methods. 2017 Jun 24. pii: S0167-7012(17)30179-3. doi: 10.1016/j.mimet.2017.06.018. [Epub ahead of print]
[Abstract] [PubMed]

Bypassing the restriction system to improve transformation of Staphylococcus epidermidis.
Costa SK, Donegan NP, Corvaglia AR, François P, Cheung AL.
J Bacteriol. 2017 May 30. pii: JB.00271-17. doi: 10.1128/JB.00271-17. [Epub ahead of print]
[Abstract] [PubMed]

Ecthyma Gangrenosum: Escherichia coli or Pseudomonas aeruginosa?
Abbas M, Emonet S, Köhler T, Renzi G, van Delden C, Schrenzel J, Hirschel B.
Front Microbiol. 2017 May 30;8:953. doi: 10.3389/fmicb.2017.00953. eCollection 2017.
[Abstract] [PubMed]

Unexpected persistence of extended-spectrum β-lactamase-producing Enterobacteriaceae in the faecal microbiota of hospitalised patients treated with imipenem.
Grall N, Lazarevic V, Gaïa N, Couffignal C, Laouénan C, Ilic-Habensus E, Wieder I, Plesiat P, Angebault C, Bougnoux ME, Armand-Lefevre L, Andremont A, Duval X, Schrenzel J.
Int J Antimicrob Agents. 2017 Jul;50(1):81-87. doi: 10.1016/j.ijantimicag.2017.02.018. Epub 2017 May 10.
[Abstract] [PubMed]

Rapid detection and ruling out of neonatal sepsis by PCR coupled with Electrospray Ionization Mass Spectrometry (PCR/ESI-MS).
Delc C, Karam O, Pfister R, Gervaix A, Renzi G, Emonet S, Schrenzel J, Posfay-Barbe KM.
Early Hum Dev. 2017 Mar 23;108:17-22. doi: 10.1016/j.earlhumdev.2017.03.004. [Epub ahead of print]
[Abstract] [PubMed]

Catheter retention as a consequence rather than a cause of unfavorable outcome in candidemia.
Damonti L, Erard V, Garbino J, Schrenzel J, Zimmerli S, Mühlethaler K, Imhof A, Zbinden R, Fehr J, Boggian K, Bruderer T, Flückiger U, Frei R, Orasch C, Conen A, Khanna N, Bregenzer T, Bille J, Lamoth F, Marchetti O, Bochud PY; Fungal Infection Network of Switzerland (FUNGINOS).
Intensive Care Med. 2017 Mar 7. doi: 10.1007/s00134-017-4737-9. [Epub ahead of print] No abstract available.
[PubMed]

The farming environment protects mice from allergen-induced skin contact hypersensitivity.
Frossard CP, Lazarevic V, Gaïa N, Leo S, Doras C, Habre W, Schrenzel J, Burger D, Eigenmann PA
Clin Exp Allergy. 2017 Feb 15. doi: 10.1111/cea.12905. [Epub ahead of print]
[Abstract] [PubMed]

Prophages and adaptation of Staphylococcus aureus ST398 to the human clinic.
Diene SM, Corvaglia AR, François P, van der Mee-Marquet N; Regional Infection Control Group of the Centre Region.
BMC Genomics. 2017 Feb 6;18(1):133. doi: 10.1186/s12864-017-3516-x.
[Abstract] [PubMed]

Messages from the first International Conference on Clinical Metagenomics (ICCMg).
Ruppé E, Greub G, Schrenzel J.
Microbes Infect. 2017 Feb 1. pii: S1286-4579(17)30019-9. doi: 10.1016/j.micinf.2017.01.005. [Epub ahead of print]
[Abstract] [PubMed]

Clonal or not clonal? Investigating hospital outbreaks of KPC-producing Klebsiella pneumoniae with whole-genome sequencing.
Ruppé E, Olearo F, Pires D, Baud D, Renzi G, Cherkaoui A, Goldenberger D, Huttner A, François P, Harbarth S, Schrenzel J.
Clin Microbiol Infect. 2017 Jan 28. pii: S1198-743X(17)30048-4. doi: 10.1016/j.cmi.2017.01.015. [Epub ahead of print]
[Abstract] [PubMed]

Emergence of blaNDM-7-Producing Enterobacteriaceae in Gabon, 2016
Moussounda M, Diene SM, Dos Santos S, Goudeau A, François P, van der Mee-Marquet N.
Emerg Infect Dis. 2017 Feb;23(2):356-358. doi: 10.3201/eid2302.161182.
[Abstract] [PubMed]

Development of in vitro resistance to chitosan is related to changes in cell envelope structure of Staphylococcus aureus.
Raafat D, Leib N, Wilmes M, François P, Schrenzel J, Sahl HG.
Carbohydr Polym. 2017 Feb 10;157:146-155. doi: 10.1016/j.carbpol.2016.09.075.
[Abstract] [PubMed]

The TIR Homologue Lies near Resistance Genes in Staphylococcus aureus, Coupling Modulation of Virulence and Antimicrobial Susceptibility.
Patot S, Rc Imbert P, Baude J, Martins Simes P, Campergue JB, Louche A, Nijland R, Bès M, Tristan A, Laurent F, Fischer A, Schrenzel J, Vandenesch F, P Salcedo S, François P, Lina G.
PLoS Pathog. 2017 Jan 6;13(1):e1006092. doi: 10.1371/journal.ppat.1006092. eCollection 2017.
[Abstract] [PubMed]


Staphylococcus aureus, phagocyte NADPH oxidase and chronic granulomatous disease.
Buvelot H, Posfay-Barbe KM, Linder P, Schrenzel J, Krause KH.
FEMS Microbiol Rev. 2016 Dec 12. pii: fuw042. [Epub ahead of print] Review.
[Abstract] [PubMed]

Antibiotic susceptibility and molecular epidemiology of Panton-Valentine leukocidin-positive meticillin-resistant Staphylococcus aureus: An international survey.
Macedo-Viñas M, Conly J, Francois P, Aschbacher R, Blanc DS, Coombs G, Daikos G, Dhawan B, Empel J, Etienne J, Figueiredo AM, George Golding Cnisp, Han L, Kim HB, Köck R, Larsen A, Layer F, Lo J, Maeda T, Mulvey M, Pantosti A, Saga T, Schrenzel J, Simor A, Skov R, Van Rijen M, Wang H, Zakaria Z, Harbarth S.
J Glob Antimicrob Resist. 2014 Mar;2(1):43-47. doi: 10.1016/j.jgar.2013.08.003.
[Abstract] [PubMed]

The detection of microbial DNA but not cultured bacteria is associated with increased mortality in patients with suspected sepsis - a prospective multi-centre European observational study.
O'Dwyer MJ, Starczewska MH, Schrenzel J, Zacharowski K, Ecker D, Sampath R, Brealey D, Singer M, Libert N, Wilks M, Vincent JL.
Clin Microbiol Infect. 2016 Nov 23. pii: S1198-743X(16)30565-1. doi: 10.1016/j.cmi.2016.11.010. [Epub ahead of print]
[Abstract] [PubMed]

Microbial Communities of Conducting and Respiratory Zones of Lung-Transplanted Patients.
Beaume M, Lazarevic V, Köhler T, Gaïa N, Manuel O, Aubert JD, Baerlocher L, Farinelli L, Gasche P, Schrenzel J, van Delden C; Swiss Transplant Cohort Study.
Front Microbiol. 2016 Nov 7;7:1749.
[Abstract] [PubMed]

Imipenem heteroresistance in nontypeable Haemophilus influenzae is linked to a combination of altered PBP3, slow drug influx and direct efflux regulation.
Cherkaoui A, Diene SM, Renzoni A, Emonet S, Renzi G, François P, Schrenzel J.
Clin Microbiol Infect. 2016 Oct 15. pii: S1198-743X(16)30468-2. doi: 10.1016/j.cmi.2016.10.009.
[Abstract] [PubMed]

Antimicrobial activity of ceftaroline against methicillin-resistant Staphylococcus aureus (MRSA) isolates collected in 2013-2014 at the Geneva University Hospitals.
Andrey DO, François P, Manzano C, Bonetti EJ, Harbarth S, Schrenzel J, Kelley WL, Renzoni A.
Eur J Clin Microbiol Infect Dis. 2016 Oct 15.
[Abstract] [PubMed]

Comparative Genomics Analysis of Streptococcus tigurinus Strains Identifies Genetic Elements Specifically and Uniquely Present in Highly Virulent Strains.
Diene SM, François P, Zbinden A, Entenza JM, Resch G.
PLoS One. 2016 Aug 9;11(8):e0160554. doi: 10.1371/journal.pone.0160554. eCollection 2016.
[Abstract] [PubMed]

Identification of mycobacterium spp. and nocardia spp. from solid and liquid cultures by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS).
Girard V, Mailler S, Welker M, Arsac M, Cellière B, Cotte-Pattat PJ, Chatellier S, Durand G, Béni AM, Schrenzel J, Miller E, Dussoulier R, Dunne WM Jr, Butler-Wu S, Saubolle MA, Sussland D, Bell M, van Belkum A, Deol P.
Diagn Microbiol Infect Dis. 2016 Aug 2. pii: S0732-8893(16)30235-8. doi: 10.1016/j.diagmicrobio.2016.07.027. [Epub ahead of print]
[Abstract] [PubMed]

Identifying Reservoirs of Infections Caused by Kingella kingae: A Case-Control Study of Oropharyngeal Carriage ofK. kingae Among Healthy Adults.
Brändle G, Spyropoulou V, Maggio AB, Anderson de la Llana R, Cherkaoui A, Renzi G, Schrenzel J, Manzano S, Ceroni D.
Pediatr Infect Dis J. 2016 Aug;35(8):869-71. doi: 10.1097/INF.0000000000001197.
[Abstract] [PubMed]

Rapid molecular determination of methicillin resistance in staphylococcal bacteraemia improves early targeted antibiotic prescribing: a randomized clinical trial.
Emonet S, Charles PG, Harbarth S, Stewardson AJ, Renzi G, Uckay I, Cherkaoui A, Rougemont M, Schrenzel J.
Clin Microbiol Infect. 2016 Jul 27. pii: S1198-743X(16)30246-4. doi: 10.1016/j.cmi.2016.07.022. [Epub ahead of print]
[Abstract] [PubMed]

Rose bengal uptake by E. faecalis and F. nucleatum and light-mediated antibacterial activity measured by flow cytometry.
Manoil D, Filieri A, Schrenzel J, Bouillaguet S.
J Photochem Photobiol B. 2016 Jun 23;162:258-265. doi: 10.1016/j.jphotobiol.2016.06.042. [Epub ahead of print]
[Abstract] [PubMed]

Mass spectrometry methods for predicting antibiotic resistance.
Charretier Y, Schrenzel J.
Proteomics Clin Appl. 2016 Jun 17. doi: 10.1002/prca.201600041. [Epub ahead of print] Review.
[Abstract] [PubMed]

Low frequency of asymptomatic carriage of toxigenic Clostridium difficile in an acute care geriatric hospital: prospective cohort study in Switzerland.
Pires D, Prendki V, Renzi G, Fankhauser C, Sauvan V, Huttner B, Schrenzel J, Harbarth S.
Antimicrob Resist Infect Control. 2016 Jun 8;5:24. doi: 10.1186/s13756-016-0123-6. eCollection 2016.
[Abstract] [PubMed]

Standard genotyping overestimates transmission of Mycobacterium tuberculosis among immigrants in a low incidence country.
Stucki D, Ballif M, Egger M, Furrer H, Altpeter E, Battegay M, Droz S, Bruderer T, Coscolla M, Borrell S, Zürcher K, Janssens JP, Calmy A, Mazza Stalder J, Jaton K, Rieder HL, Pfyffer GE, Siegrist HH, Hoffmann M, Fehr J, Dolina M, Frei R, Schrenzel J, Böttger EC, Gagneux S, Fenner L; Swiss HIV Cohort and Molecular Epidemiology of Tuberculosis Study Groups.
J Clin Microbiol. 2016 May 18. pii: JCM.00126-16. [Epub ahead of print]
[Abstract] [PubMed]

Predictors of Heavy Stethoscope Contamination Following a Physical Examination.
Tschopp C, Schneider A, Longtin Y, Renzi G, Schrenzel J, Pittet D.
Infect Control Hosp Epidemiol. 2016 Jun;37(6):673-9. doi: 10.1017/ice.2016.40.
[Abstract] [PubMed]

Enigmatic occurrence of NDM-7 enzyme in the community.
van der Mee-Marquet N, Diene S, Chopin F, Goudeau A, François P.
Int J Antimicrob Agents. 2016 Apr 22. pii: S0924-8579(16)30048-6. doi: 10.1016/j.ijantimicag.2016.04.002. [Epub ahead of print]
[PubMed]

Impact of Hypocaloric Hyperproteic Diet on Gut Microbiota in Overweight or Obese Patients with Nonalcoholic Fatty Liver Disease: A Pilot Study.
Pataky Z, Genton L, Spaht L, Lazarevic V, Terraz S, Gaïa N, Rubbia-Brandt L, Golay A, Schrenzel J, Pichard C.
Dig Dis Sci. 2016 May 3. [Epub ahead of print]
[Abstract] [PubMed]

Decontamination of 16S rRNA gene amplificon sequence datasets based on bacterial load assessment by qPCR.
Lazarevic V, Gaïa N, Girard M, Schrenzel J.
BMC Microbiol. 2016 Apr 23;16(1):73. doi: 10.1186/s12866-016-0689-4.
[Abstract] [PubMed]

Clinical metagenomics for the management of hospital- and healthcare-acquired pneumonia.
Ruppé E, Baud D, Schicklin S, Guignon G, Schrenzel J.
Future Microbiol. 2016 Mar 2.[Epub ahead of print]
[Abstract] [PubMed]

Daptomycin tolerance in the Staphylococcus aureus pitA6 mutant is due to upregulation of the dlt-operon.
Mechler L, Bonetti EJ, Reichert S, Flötenmeyer M, Schrenzel J, Bertram R, François P, Götz F.
Antimicrob Agents Chemother. 2016 Feb 16. pii: AAC.03022-15. [Epub ahead of print]
[Abstract] [PubMed]

Determinants of Successful Methicillin-Resistant Staphylococcus aureus Decolonization.
von Dach E, Landelle C, Agostinho A, Haustein T, François P, Renzi G, Schrenzel J, Harbarth S.
Infect Control Hosp Epidemiol. 2016 Feb 16:1-4. [Epub ahead of print] No abstract available.
[PubMed]

Lactic Acid Bacteria Isolated from Bovine Mammary Microbiota: Potential Allies against Bovine Mastitis.
Bouchard DS, Seridan B, Saraoui, Rault L, Germon P, Gonzalez-Moreno C, Nader-Macias FM, Baud D, François P, Chuat V, Chain F, Langella P, Nicoli J, Le Loir Y, Even S.
PLoS One. 2015 Dec 29;10(12):e0144831. doi: 10.1371/journal.pone.0144831. eCollection 2015.
[Abstract] [PubMed]

Characterization of RNA helicase CshA and its role in protecting mRNAs and sRNAs of Staphylococcus aureus strain Newman.
Kim S, Corvaglia AR, Léo S, Cheung A, Francois P.
Infect Immun. 2016 Jan 11. pii: IAI.01042-15. [Epub ahead of print]
[Abstract] [PubMed]


Effect of Periodontal Therapy With Amoxicillin-Metronidazole on Pharyngeal Carriage of Penicillin- and Erythromycin-Resistant Viridans Streptococci.
Mombelli A, Cionca N, Almaghlouth A, Cherkaoui A, Schrenzel J, Giannopoulou C.
J Periodontol. 2015 Dec 14:1-13. [Epub ahead of print]
[Abstract] [PubMed]

Xpert(®) MTB/RIF assay sensitivity with different methods of CSF processing for the diagnosis of TB meningitis.
Andrey DO, Hinrikson H, Renzi G, Hibbs J, Adler D, Schrenzel J.
Int J Tuberc Lung Dis. 2015 Dec;19(12):1555-6. doi: 10.5588/ijtld.15.0556. No abstract available.
[PubMed]

Randomized, placebo-controlled, double-blind clinical trial to evaluate the efficacy of polyhexanide for topical decolonization of MRSA carriers.
Landelle C, von Dach E, Haustein T, Agostinho A, Renzi G, Renzoni A, Pittet D, Schrenzel J, François P, Harbarth S.
J Antimicrob Chemother. 2015 Oct 27. pii: dkv331. [Epub ahead of print].
[Abstract] [PubMed]

Comparative genomics of community-associated methicillin-resistant Staphylococcus aureus shows the emergence of ST8-USA300 clone in Geneva, Switzerland.
Von Dach E, Diene SM, Fankhauser C, Schrenzel J, Harbarth S, François P.
J Infect Dis. 2015 Oct 13. pii: jiv489. [Epub ahead of print]
[Abstract] [PubMed]

Characteristics of multidrug-resistant Acinetobacter baumannii strains isolated in Geneva during colonization or infection.
Cherkaoui A, Emonet S, Renzi G, Schrenzel J.
Ann Clin Microbiol Antimicrob. 2015 Sep 11;14(1):42.
[Abstract] [PubMed]

Rapid Diagnosis of Infection in the Critically Ill, a Multicenter Study of Molecular Detection in Bloodstream Infections, Pneumonia, and Sterile Site Infections.
Vincent JL, Brealey D, Libert N, Abidi NE, O'Dwyer M, Zacharowski K, Mikaszewska-Sokolewicz M, Schrenzel J, Simon F, Wilks M, Picard-Maureau M, Chalfin DB, Ecker DJ, Sampath R, Singer M; Rapid Diagnosis of Infections in the Critically Ill Team.
Crit Care Med. 2015 Aug 31. [Epub ahead of print]
[Abstract] [PubMed]

Repeated exposures to blue light-activated eosin Y enhance inactivation of E. faecalis biofilms, in vitro.
Marinic K, Manoil D, Filieri A, Wataha JC, Schrenzel J, Lange N, Bouillaguet S.
Photodiagnosis Photodyn Ther. 2015 Jul 15. pii: S1572-1000(15)00074-5. doi: 10.1016/j.pdpdt.2015.06.004. [Epub ahead of print]
[Abstract] [PubMed]

Ampicillin-resistant Haemophilus influenzae isolates in Geneva: serotype, antimicrobial susceptibility, and β-lactam resistance mechanisms.
Cherkaoui A, Diene SM, Emonet S, Renzi G, Francois P, Schrenzel J.
Eur J Clin Microbiol Infect Dis. 2015 Jul 18. [Epub ahead of print]
[Abstract] [PubMed]

Oropharyngeal K. kingae carriage in children: characteristics and correlation with osteoarticular infections.
Anderson de la Llana R, Dubois-Ferriere V, Maggio A, Cherkaoui A, Manzano S, Renzi G, Hibbs J, Schrenzel J, Ceroni D.
Pediatr Res. 2015 Jul 17. doi: 10.1038/pr.2015.133. [Epub ahead of print]
[Abstract] [PubMed]

Diagnosis of bacterial gastroenteritis.
Cherkaoui A, Emonet S, Renzi G, Schrenzel J.
Rev Med Suisse. 2015 Apr 15;11(470):856-61. French.
[Abstract] [PubMed]

Confident identification of filamentous fungi by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry without subculture-based sample preparation.
Riat A, Hinrikson H, Barras V, Fernandez J, Schrenzel J.
Int J Infect Dis. 2015 Apr 23. pii: S1201-9712(15)00099-5. doi: 10.1016/j.ijid.2015.04.013. [Epub ahead of print] No abstract available.
[PubMed]

Groundsteel target plates in combination with direct transfer of clinical yeast isolates improves frequencies of species level MALDITOF MS identifications in comparison with polished steel target plates.
Riat A, Rentenaar RJ, van Drongelen AM, Barras V, Bertens LC, Vlek AL, Doppenberg E, Weersink AJ, Reinders E, Vlaminckx BJ, Overbeeke N, van Burgel ND, Peterse N, Bosboom R, Boekhout T, Schrenzel J, Kusters JG.
J Clin Microbiol. 2015 Mar 25. pii: JCM.03632-14
[Abstract] [PubMed]

Label-free SRM-based relative quantification of antibiotic resistance mechanisms in Pseudomonas aeruginosa clinical isolates.
Charretier Y, Köhler T, Cecchini T, Bardet C, Cherkaoui A, Llanes C, Bogaerts P, Chatellier S, Charrier JP, Schrenzel J.
Front Microbiol. 2015 Feb 10;6:81. doi: 10.3389/fmicb.2015.00081. eCollection 2015.
[Abstract] [PubMed]

Mapping axillary microbiota responsible for body odours using a culture-independent approach.
Troccaz M, Gaïa N, Beccucci S, Schrenzel J, Cayeux I, Starkenmann C, Lazarevic V.
Microbiome. 2015 Jan 24;3(1):3. doi: 10.1186/s40168-014-0064-3. eCollection 2015.
[Abstract] [PubMed]

Collateral damage from oral ciprofloxacin versus nitrofurantoin in outpatients with urinary tract infections: a culture-free analysis of gut microbiota.
Stewardson AJ, Gaïa N, François P, Malhotra-Kumar S, Delémont C, Martinez de Tejada B, Schrenzel J, Harbarth S, Lazarevic V; for the SATURN WP1 and WP3 Study Groups.
Clin Microbiol Infect. 2014 Nov 25. pii: S1198-743X(14)00102-5. doi: 10.1016/j.cmi.2014.11.016. [Epub ahead of print]
[Abstract] [PubMed]

Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis(1.).
Gayet-Ageron A, Sednaoui P, Lautenschlager S, Ferry T, Toutous-Trellu L, Cavassini M, Yassir F, Martinez de Tejada B, Emonet S, Combescure C, Schrenzel J, Perneger T.
Emerg Infect Dis. 2015;21(1):127-9. doi: 10.3201/eid2101.140790.
[Abstract] [PubMed]



Bacterial genomics and metagenomics: clinical applications and medical relevance.
Diene SM, Bertelli C, Pillonel T, Schrenzel J, Greub G.
Rev Med Suisse. 2014 Nov 12;10(450):2155-61. French.
[Abstract] [PubMed]

Which benefits for the clinician to implement MALDI-TOF/MS in the bacteriology laboratory?
Riat A, Cherkaoui A, Emonet S, Greub G, Schrenzel J.
Rev Med Suisse. 2014 Nov 12;10(450):2149-54. French.
[Abstract] [PubMed]

ESBL and carbapenemases in Enterobacteriaceae.
Cherkaoui A, Emonet S, Renzi G, Riat A, Greub G, Schrenzel J.
Rev Med Suisse. 2014 Nov 12;10(450):2142-8. French.
[Abstract] [PubMed]

Rapid tests during respiratory infection: an aid to non-prescription of antibiotics?
Emonet S, Cherkaoui A, Riat A, Greub G, Schrenzel J.
Rev Med Suisse. 2014 Nov 12;10(450):2137-41. French.
[Abstract] [PubMed]

Diagnostic approach of intracellular bacteria and fastidious microorganisms.
Lamoth F, Schrenzel J, Greub G.
Rev Med Suisse. 2014 Nov 12;10(450):2130-6. French.
[Abstract] [PubMed]

Microbiological diagnosis of pneumonia.
Jaton K, Schrenzel J, Greub G.
Rev Med Suisse. 2014 Nov 12;10(450):2126-9. French.
[Abstract] [PubMed]

Le nouveau visage de la microbiologie diagnostique.
Greub G, Schrenzel J.
Rev Med Suisse. 2014 Nov 12;10(450):2123-4. French.
[Abstract] [PubMed]

Polymerase-chain reaction/electrospray ionization-mass spectrometry for the detection of bacteria and fungi in bronchoalveolar lavage fluids: a prospective observational study.
Huttner A, Emonet S, Harbarth S, Renzi G, Kaiser L, Schrenzel J.
Clin Microbiol Infect. 2014 Dec 19. doi: 10.1111/1469-0691.12749. [Epub ahead of print]
[Abstract] [PubMed]

Performance of the 47kDa protein membrane versus DNA polymerase I genes for detection of Treponema pallidum by polymerase chain reaction in ulcers.
Gayet-Ageron A, Laurent F, Schrenzel J, Charton B, Jimenez-Getaz G, Tangomo M, Ferry T, Sednaoui P, Lautenschlager S, Toutous-Trellu L, Martinez de Tejada B, Cavassini M, Emonet S, Perneger T, Salord H.
J Clin Microbiol. 2014 Dec 17. pii: JCM.03444-14. [Epub ahead of print]
[Abstract] [PubMed]

Modelling antibiotic and cytotoxic isoquinoline effects in Staphylococcus aureus, Staphylococcus epidermidis and mammalian cells.
Cecil A, Ohlsen K, Menzel T, François P, Schrenzel J, Fischer A, Dörries K, Selle M, Lalk M, Hantzschmann J, Dittrich M, Liang C, Bernhardt J, Olschläger TA, Bringmann G, Bruhn H, Unger M, Ponte-Sucre A, Lehmann L, Dandekar T.
Int J Med Microbiol. 2014 Nov 27. pii: S1438-4221(14)00154-4. doi: 10.1016/j.ijmm.2014.11.006. [Epub ahead of print]
[Abstract] [PubMed]

Noma Affected Children from Niger Have Distinct Oral Microbial Communities Based on High-Throughput Sequencing of 16S rRNA Gene Fragments.
Whiteson KL, Lazarevic V, Tangomo-Bento M, Girard M, Maughan H, Pittet D, Francois P, Schrenzel J; the GESNOMA study group.
PLoS Negl Trop Dis. 2014 Dec 4;8(12):e3240. doi: 10.1371/journal.pntd.0003240. eCollection 2014.
[Abstract] [PubMed]

Relapse of Tropheryma whipplei endocarditis treated by trimethoprim/sulfamethoxazole, cured by hydroxychloroquine plus doxycycline.
Emonet S, Wuillemin T, Harbarth S, Wassilew N, Cikirikcioglu M, Schrenzel J, Lagier JC, Raoult D, van Delden C.
Int J Infect Dis. 2014 Nov 6;30C:17-19. doi: 10.1016/j.ijid.2014.11.003. [Epub ahead of print]
[Abstract] [PubMed]

Alterations of gut barrier and gut microbiota in food restriction, food deprivation and protein-energy wasting.
Genton L, Cani PD, Schrenzel J.
Clin Nutr. 2014 Oct 12. pii: S0261-5614(14)00255-6. doi: 10.1016/j.clnu.2014.10.003. [Epub ahead of print] Review.
[Abstract] [PubMed]

Accelerated Photoactivated Chromophore for Keratitis-Corneal Collagen Cross-linking as a First-line and Sole Treatment in Early Fungal Keratitis.
Tabibian D, Richoz O, Riat A, Schrenzel J, Hafezi F.
J Refract Surg. 2014 Dec 1;30(12):855-857. doi: 10.3928/1081597X-20141113-06.
[Abstract] [PubMed]

Antibacterial Efficacy of Accelerated Photoactivated Chromophore for Keratitis-Corneal Collagen Cross-linking (PACK-CXL).
Richoz O, Kling S, Hoogewoud F, Hammer A, Tabibian D, Francois P, Schrenzel J, Hafezi F.
J Refract Surg. 2014 Dec 1;30(12):850-854. doi: 10.3928/1081597X-20141118-01.
[Abstract] [PubMed]

Staphylococcus epidermidis SrrAB regulates bacterial growth and biofilm formation differently under oxic and micro-aerobic conditions.
Wu Y, Wu Y, Zhu T, Han H, Liu H, Xu T, Francois P, Fischer A, Bai L, Götz F, Qu D.
J Bacteriol. 2014 Nov 17. pii: JB.02231-14. [Epub ahead of print]
[Abstract] [PubMed]